In 1958, she recorded "Going to Heaven to Meet the King", with the Southwest Michigan State Choir, becoming the first person to commit the sounds of a choir to record. She was also the first person to separate vocal parts into soprano, alto and tenor. She received three gold albums with the Southwest Michigan State Choir, and went on to write and arrange hundreds of songs and recorded over 50 albums. She directed Cadillac Motor Company's Christmas choir for 11 years and also conducted community-wide mass choirs for the prestigious NAACP Freedom Fund Dinners.

In 1979, she founded the Clark Conservatory of Music in Detroit, which established itself as one of the most prestigious schools of its kind in the country. In 1981, Trinity College in Pennsylvania conferred upon her one of their highest honors, the degree of Doctor of Humanities. After the death of Bishop Bailey in 1985, she continued as State Minister of Music for Southwest Michigan Jurisdiction #1, attending Greater Mitchell Church of God in Christ, under Bishop J.H. Sheard.

She was an editor and contributor to the hymnal published by the Church of God in Christ entitled, Yes, Lord. When the late Bishop J.O. Patterson appointed her the International President of the Music Department in 1968, she worked to instill within musicians and choirs a responsibility to Christ as well as capability for Christ. Throughout her efforts, young people especially received her and many were saved, filled with the Holy Ghost, and uplifted by her music and message.

She completely revolutionized the music departments. She gave definition to the role of State Minister of Music, traveled year-round to every state in the country conducting workshops, rehearsals and musicals to prepare choirs for service on the National Church level and organized the structure of the National Music Convention of the Church of God in Christ.

Dr. Clark introduced the workshop and seminar concept to the convention, and, along with her staff, structured classes for the convention and created "A Song Is Born", the program where new talent was introduced before thousands.